Gene
exosc4
- ID
- ZDB-GENE-040426-1702
- Name
- exosome component 4
- Symbol
- exosc4 Nomenclature History
- Previous Names
-
- exosome complex exonuclease RRP41 (1)
- zgc:73175
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable exonuclease activity. Predicted to be involved in RNA metabolic process. Predicted to be part of cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Predicted to be active in nucleolus. Is expressed in several structures, including alar plate midbrain region; immature eye; midbrain; pectoral fin bud; and segmental plate. Orthologous to human EXOSC4 (exosome component 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73175 (15 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001247 | Exoribonuclease, phosphorolytic domain 1 |
| Domain | IPR015847 | Exoribonuclease, phosphorolytic domain 2 |
| Family | IPR050080 | Ribonuclease PH |
| Homologous_superfamily | IPR020568 | Ribosomal protein uS5 domain 2-type superfamily |
| Homologous_superfamily | IPR027408 | PNPase/RNase PH domain superfamily |
| Homologous_superfamily | IPR036345 | Exoribonuclease, PH domain 2 superfamily |
Domain Details Per Protein
| Protein | Length | Exoribonuclease, PH domain 2 superfamily | Exoribonuclease, phosphorolytic domain 1 | Exoribonuclease, phosphorolytic domain 2 | PNPase/RNase PH domain superfamily | Ribonuclease PH | Ribosomal protein uS5 domain 2-type superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6PBZ8
|
245 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
exosc4-201
(1)
|
Ensembl | 782 nt |
Interactions and Pathways
No data available
Plasmids
No data available