Gene

bcl6aa

ID

ZDB-GENE-040426-1696

Name

BCL6A transcription repressor a

Symbol

bcl6aa Nomenclature History

Previous Names

bcl6
bcl6a
zgc:73162

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to have metal ion binding activity and nucleic acid binding activity. Involved in negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator and retina morphogenesis in camera-type eye. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in B-cell lymphoma and diffuse large B-cell lymphoma. Is expressed in brain; eye; and myotome. Orthologous to human BCL6 (BCL6 transcription repressor).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:73162 (8 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 6 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With bcl6aa Human Ortholog

No data available

Associated With bcl6aa Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000210	BTB/POZ domain
Domain	IPR013087	Zinc finger C2H2-type
Homologous_superfamily	IPR011333	SKP1/BTB/POZ domain superfamily
Homologous_superfamily	IPR036236	Zinc finger C2H2 superfamily