Gene

rims2a

ID

ZDB-GENE-040426-1656

Name

regulating synaptic membrane exocytosis 2a

Symbol

rims2a Nomenclature History

Previous Names

rims2
zgc:73064

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to be a structural constituent of presynaptic active zone. Predicted to be involved in regulation of synaptic vesicle exocytosis; synaptic vesicle docking; and synaptic vesicle priming. Predicted to act upstream of or within exocytosis and intracellular protein transport. Predicted to be located in membrane and synapse. Predicted to be active in presynaptic active zone cytoplasmic component and presynaptic membrane. Is expressed in nervous system and pancreatic system. Orthologous to human RIMS2 (regulating synaptic membrane exocytosis 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:73064 (9 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rims2a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Cone-rod synaptic disorder syndrome, congenital nonprogressive	618970

Associated With rims2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000008	C2 domain
Family	IPR039032	Rim-like
Homologous_superfamily	IPR035892	C2 domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M9NZV4	InterPro	1473
UniProtKB:A0A8M6YTP4	InterPro	1347
UniProtKB:A0A8M9PDV7	InterPro	308
UniProtKB:A0A8M9PNB2	InterPro	286
UniProtKB:A0A8M9P8J7	InterPro	313
UniProtKB:A0A8M9PKA5	InterPro	1397
UniProtKB:A0A8M3AIH2	InterPro	1512
UniProtKB:A0AB32T550	InterPro	1622
UniProtKB:A0AB32TAK7	InterPro	1558