Gene

klc1a

ID
ZDB-GENE-040426-1599
Name
kinesin light chain 1a
Symbol
klc1a Nomenclature History
Previous Names
  • zgc:66299 (1)
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have microtubule motor activity. Predicted to localize to kinesin complex. Human ortholog(s) of this gene implicated in Alzheimer's disease and relapsing-remitting multiple sclerosis. Is expressed in central nervous system; cranial ganglion; neurons; retina; and retinal ganglion cell layer. Orthologous to human KLC1 (kinesin light chain 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With klc1a Human Ortholog
No data available
Associated With klc1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR002151 Kinesin light chain
Homologous_superfamily IPR011990 Tetratricopeptide-like helical domain superfamily
Repeat IPR015792 Kinesin light chain repeat
Repeat IPR019734 Tetratricopeptide repeat
Domain Details Per Protein
Protein Length Kinesin light chain Kinesin light chain repeat Tetratricopeptide-like helical domain superfamily Tetratricopeptide repeat
UniProtKB:A0A8M2B3J0 647
UniProtKB:A0A8M2B2P5 557
UniProtKB:A0A8M2B2S3 548
UniProtKB:F1QS14 605
UniProtKB:Q7SXI2 538
UniProtKB:A0A8M3AYZ1 638
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA klc1a-201 (1) Ensembl 1,819 nt
mRNA klc1a-202 (1) Ensembl 2,164 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations