Gene
prpf31
- ID
- ZDB-GENE-040426-1561
- Name
- PRP31 pre-mRNA processing factor 31 homolog (yeast)
- Symbol
- prpf31 Nomenclature History
- Previous Names
-
- zgc:66177 (1)
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have U4atac snRNA binding activity. Involved in mRNA splicing, via spliceosome and retina development in camera-type eye. Predicted to localize to nucleus. Used to study retinitis pigmentosa. Human ortholog(s) of this gene implicated in retinitis pigmentosa 11. Is expressed in retina and retinal neural layer. Orthologous to human PRPF31 (pre-mRNA processing factor 31).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:66177 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 15 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| retinitis pigmentosa 11 | Alliance | Retinitis pigmentosa 11 | 600138 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| retinitis pigmentosa | WT + MO1-prpf31 | standard conditions | (2) |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Nop, C-terminal domain | Nop domain | Nop domain superfamily | NOSIC | Prp31 C-terminal | U4/U6 small nuclear ribonucleoprotein Prp31 |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7SXM7
|
508 | ||||||
|
UniProtKB:B2GS36
|
508 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
prpf31-201
(1)
|
Ensembl | 1,867 nt | ||
| mRNA |
prpf31-202
(1)
|
Ensembl | 908 nt | ||
| mRNA |
prpf31-203
(1)
|
Ensembl | 1,542 nt |
Interactions and Pathways
No data available
Plasmids
No data available