Gene

nat10

ID

ZDB-GENE-040426-1543

Name

N-acetyltransferase 10

Symbol

nat10 Nomenclature History

Previous Names

zgc:66119 (1)

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Predicted to enable 18S rRNA cytidine N-acetyltransferase activity; tRNA N4-acetyltransferase activity; and tRNA binding activity. Predicted to be involved in rRNA acetylation involved in maturation of SSU-rRNA; tRNA acetylation; and tRNA wobble cytosine modification. Predicted to act upstream of or within rRNA processing and tRNA processing. Predicted to be located in nucleus. Predicted to be active in nucleolus. Is expressed in several structures, including alar plate midbrain region; immature eye; nervous system; neural plate; and segmental plate. Orthologous to human NAT10 (N-acetyltransferase 10).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:66119 (11 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Yang et al., 2024
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nat10 Human Ortholog

No data available

Associated With nat10 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000182	GNAT domain
Domain	IPR013562	tRNA(Met) cytidine acetyltransferase TmcA, N-terminal
Domain	IPR027992	Possible tRNA binding domain
Family	IPR032672	TmcA/NAT10/Kre33
Family	IPR033688	RNA cytidine acetyltransferase NAT10
Homologous_superfamily	IPR016181	Acyl-CoA N-acyltransferase
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase

Domain Details Per Protein

Protein	Length	Acyl-CoA N-acyltransferase	GNAT domain	P-loop containing nucleoside triphosphate hydrolase	Possible tRNA binding domain	RNA cytidine acetyltransferase NAT10	TmcA/NAT10/Kre33	tRNA(Met) cytidine acetyltransferase TmcA, N-terminal
UniProtKB:Q6PFQ5 InterPro	1025

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	nat10-201 (1) Ensembl	Ensembl	3,341 nt	Select Tool ZFIN BLAST
mRNA	nat10-203 (1) Ensembl	Ensembl	6,663 nt	Select Tool ZFIN BLAST
ncRNA	nat10-002 (1) Ensembl	Ensembl	737 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations