Gene

rad23b

ID

ZDB-GENE-040426-1487

Name

RAD23 homolog B, nucleotide excision repair protein

Symbol

rad23b Nomenclature History

Previous Names

HR23B (1)
zgc:65951

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to enable polyubiquitin modification-dependent protein binding activity; proteasome binding activity; and ubiquitin binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within DNA repair. Predicted to be located in cytoplasm and nucleus. Predicted to be part of proteasome complex. Predicted to be active in cytosol and nucleoplasm. Is expressed in liver. Orthologous to human RAD23B (RAD23 homolog B, nucleotide excision repair protein).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:65951 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rad23b Human Ortholog

No data available

Associated With rad23b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000626	Ubiquitin-like domain
Domain	IPR006636	Heat shock chaperonin-binding
Domain	IPR015360	XPC-binding domain
Domain	IPR015940	Ubiquitin-associated domain
Domain	IPR041811	RAD23A/RAD23B, UBA1 domain
Family	IPR004806	UV excision repair protein Rad23
Homologous_superfamily	IPR009060	UBA-like superfamily
Homologous_superfamily	IPR029071	Ubiquitin-like domain superfamily
Homologous_superfamily	IPR036353	XPC-binding domain superfamily

Domain Details Per Protein

Protein	Length	Heat shock chaperonin-binding	RAD23A/RAD23B, UBA1 domain	UBA-like superfamily	Ubiquitin-associated domain	Ubiquitin-like domain	Ubiquitin-like domain superfamily	UV excision repair protein Rad23	XPC-binding domain	XPC-binding domain superfamily
UniProtKB:A0A2R8PYT0 InterPro	381

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	rad23b-201 (1) Ensembl	Ensembl		1,599 nt	Select Tool ZFIN BLAST
mRNA	rad23b-202 (1) Ensembl	Ensembl		1,982 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations