Gene
ggt1a
- ID
- ZDB-GENE-040426-1388
- Name
- gamma-glutamyltransferase 1a
- Symbol
- ggt1a Nomenclature History
- Previous Names
-
- ggt1
- zgc:64172 (1)
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have glutathione hydrolase activity and peptidyltransferase activity. Predicted to be involved in several processes, including peptide metabolic process; response to estradiol; and response to lipopolysaccharide. Predicted to localize to plasma membrane. Human ortholog(s) of this gene implicated in gamma-glutamyl transpeptidase deficiency. Is expressed in lens and solid lens vesicle. Orthologous to human GGT1 (gamma-glutamyltransferase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:64172 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| gamma-glutamyl transpeptidase deficiency | Alliance | ?Glutathioninuria | 231950 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR000101 | Gamma-glutamyltranspeptidase |
| Homologous_superfamily | IPR029055 | Nucleophile aminohydrolases, N-terminal |
| Homologous_superfamily | IPR043137 | Gamma-glutamyltranspeptidase, small subunit |
| Homologous_superfamily | IPR043138 | Gamma-glutamyltranspeptidase, large subunit, C-terminal domain |
Domain Details Per Protein
| Protein | Length | Gamma-glutamyltranspeptidase | Gamma-glutamyltranspeptidase, large subunit, C-terminal domain | Gamma-glutamyltranspeptidase, small subunit | Nucleophile aminohydrolases, N-terminal |
|---|---|---|---|---|---|
|
UniProtKB:Q7T2A1
|
489 | ||||
|
UniProtKB:A0A8M6YZQ0
|
619 |
Interactions and Pathways
No data available
Plasmids
No data available