Gene
rtn4ip1
- ID
- ZDB-GENE-040426-1314
- Name
- reticulon 4 interacting protein 1
- Symbol
- rtn4ip1 Nomenclature History
- Previous Names
-
- zgc:63964
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have oxidoreductase activity. Involved in eye photoreceptor cell development and retina layer formation. Predicted to localize to mitochondrial outer membrane. Human ortholog(s) of this gene implicated in optic atrophy 10. Orthologous to human RTN4IP1 (reticulon 4 interacting protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63964 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Angebault et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| optic atrophy 10 | Alliance | Optic atrophy 10 with or without ataxia, impaired intellectual development and seizures | 616732 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR013154 | Alcohol dehydrogenase-like, N-terminal |
| Domain | IPR020843 | Polyketide synthase, enoylreductase domain |
| Family | IPR037397 | Reticulon-4-interacting protein 1 |
| Family | IPR050700 | YIM1 and Zinc-containing Alcohol Dehydrogenase Families |
| Homologous_superfamily | IPR011032 | GroES-like superfamily |
| Homologous_superfamily | IPR036291 | NAD(P)-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Alcohol dehydrogenase-like, N-terminal | GroES-like superfamily | NAD(P)-binding domain superfamily | Polyketide synthase, enoylreductase domain | Reticulon-4-interacting protein 1 | YIM1 and Zinc-containing Alcohol Dehydrogenase Families |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7T3C7
|
387 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rtn4ip1-201
(1)
|
Ensembl | 1,370 nt |
Interactions and Pathways
No data available
Plasmids
No data available