Gene
ddb1
- ID
- ZDB-GENE-040426-1272
- Name
- damage-specific DNA binding protein 1
- Symbol
- ddb1 Nomenclature History
- Previous Names
-
- zgc:63840
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have damaged DNA binding activity. Involved in negative regulation of apoptotic process and regulation of cell cycle process. Predicted to localize to cullin-RING ubiquitin ligase complex and nucleus. Is expressed in blastomere; endoderm; nervous system; pharyngeal arch; and somite. Orthologous to human DDB1 (damage specific DNA binding protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Hu et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| White-Kernohan syndrome | 619426 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR004871 | Cleavage/polyadenylation specificity factor, A subunit, C-terminal |
| Domain | IPR018846 | Cleavage/polyadenylation specificity factor, A subunit, N-terminal |
| Family | IPR050358 | RSE1/DDB1/CFT1/CPSF1 |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
Domain Details Per Protein
| Protein | Length | Cleavage/polyadenylation specificity factor, A subunit, C-terminal | Cleavage/polyadenylation specificity factor, A subunit, N-terminal | RSE1/DDB1/CFT1/CPSF1 | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q6PGT6
|
897 |
Interactions and Pathways
No data available
Plasmids
No data available