Gene
xpa
- ID
- ZDB-GENE-040426-1205
- Name
- xeroderma pigmentosum, complementation group A
- Symbol
- xpa Nomenclature History
- Previous Names
-
- zgc:63640
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have damaged DNA binding activity. Predicted to be involved in DNA repair. Predicted to localize to nucleotide-excision repair factor 1 complex. Human ortholog(s) of this gene implicated in xeroderma pigmentosum and xeroderma pigmentosum group A. Is expressed in liver. Orthologous to human XPA (XPA, DNA damage recognition and repair factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| xeroderma pigmentosum group A | Alliance | Xeroderma pigmentosum, group A | 278700 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR022652 | Zinc finger, XPA-type, conserved site |
| Domain | IPR022656 | XPA, C-terminal |
| Domain | IPR027838 | Domain of unknown function DUF4585 |
| Family | IPR000465 | XPA/RAD14 |
| Homologous_superfamily | IPR009061 | Putative DNA-binding domain superfamily |
| Homologous_superfamily | IPR037129 | XPA domain superfamily |
Domain Details Per Protein
| Protein | Length | Domain of unknown function DUF4585 | Putative DNA-binding domain superfamily | XPA, C-terminal | XPA domain superfamily | XPA/RAD14 | Zinc finger, XPA-type, conserved site |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3AY35
|
277 | ||||||
|
UniProtKB:Q7SY02
|
549 | ||||||
|
UniProtKB:A0A8M3BDZ6
|
276 |
Interactions and Pathways
No data available
Plasmids
No data available