Gene

sh2d3cb

ID
ZDB-GENE-040426-1052
Name
SH2 domain containing 3Cb
Symbol
sh2d3cb Nomenclature History
Previous Names
  • sh2d3c
  • zgc:56490 (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have guanyl-nucleotide exchange factor activity. Predicted to be involved in positive regulation of peptidyl-serine phosphorylation. Is expressed in nervous system; neural tube; and trigeminal placode. Orthologous to human SH2D3C (SH2 domain containing 3C).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sh2d3cb Human Ortholog
No data available
Associated With sh2d3cb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000980 SH2 domain
Domain IPR001895 Ras guanine-nucleotide exchange factors catalytic domain
Domain IPR044102 SHEP1/BCAR3/NSP1, SH2 domain
Family IPR051853 Adapter protein with SH2 and Ras-GEF domains
Homologous_superfamily IPR023578 Ras guanine nucleotide exchange factor domain superfamily
Homologous_superfamily IPR036860 SH2 domain superfamily
Homologous_superfamily IPR036964 Ras guanine-nucleotide exchange factor, catalytic domain superfamily
Domain Details Per Protein
Protein Length Adapter protein with SH2 and Ras-GEF domains Ras guanine-nucleotide exchange factor, catalytic domain superfamily Ras guanine nucleotide exchange factor domain superfamily Ras guanine-nucleotide exchange factors catalytic domain SH2 domain SH2 domain superfamily SHEP1/BCAR3/NSP1, SH2 domain
UniProtKB:A0A8M2BCW0 629
UniProtKB:Q7ZUD0 635
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA sh2d3cb-201 (1) Ensembl 659 nt
mRNA sh2d3cb-202 (1) Ensembl 694 nt
mRNA sh2d3cb-203 (1) Ensembl 2,537 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations