Gene
med17
- ID
- ZDB-GENE-040302-1
- Name
- mediator complex subunit 17
- Symbol
- med17 Nomenclature History
- Previous Names
-
- crsp6
- zgc:153983
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to localize to core mediator complex and mediator complex. Human ortholog(s) of this gene implicated in infantile cerebral and cerebellar atrophy with postnatal progressive microcephaly. Orthologous to human MED17 (mediator complex subunit 17).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Wang et al., 2006
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| infantile cerebral and cerebellar atrophy with postnatal progressive microcephaly | Alliance | Microcephaly, postnatal progressive, with seizures and brain atrophy | 613668 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR019313 | Mediator complex, subunit Med17 |
Domain Details Per Protein
| Protein | Length | Mediator complex, subunit Med17 |
|---|---|---|
|
UniProtKB:E7FGV8
|
||
|
UniProtKB:Q08BY1
|
643 | |
|
UniProtKB:B2GSS8
|
643 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance