Gene
gnmt
- ID
- ZDB-GENE-040227-1
- Name
- glycine N-methyltransferase
- Symbol
- gnmt Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable cation binding activity; glycine N-methyltransferase activity; and identical protein binding activity. Predicted to be involved in several processes, including alpha-amino acid metabolic process; protein homotetramerization; and regulation of gluconeogenesis. Predicted to act upstream of or within methylation. Predicted to be active in cytosol. Is expressed in spinal cord. Human ortholog(s) of this gene implicated in glycine N-methyltransferase deficiency. Orthologous to human GNMT (glycine N-methyltransferase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Newman et al., 2009
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| glycine N-methyltransferase deficiency | Alliance | Glycine N-methyltransferase deficiency | 606664 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Glycine/Sarcosine N-methyltransferase | Methyltransferase domain | S-adenosyl-L-methionine-dependent methyltransferase superfamily |
|---|---|---|---|---|
|
UniProtKB:Q6P607
|
294 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available