Gene
sarm1
- ID
- ZDB-GENE-040219-1
- Name
- sterile alpha and TIR motif containing 1
- Symbol
- sarm1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Enables NAD+ nucleosidase activity. Involved in NAD catabolic process. Acts upstream of or within regulation of axon regeneration. Predicted to be located in axon; mitochondrion; and synapse. Predicted to be active in dendrite. Orthologous to human SARM1 (sterile alpha and TIR motif containing 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000157 | Toll/interleukin-1 receptor homology (TIR) domain |
| Domain | IPR001660 | Sterile alpha motif domain |
| Family | IPR039184 | Sterile alpha and TIR motif-containing protein 1 |
| Homologous_superfamily | IPR011989 | Armadillo-like helical |
| Homologous_superfamily | IPR013761 | Sterile alpha motif/pointed domain superfamily |
| Homologous_superfamily | IPR016024 | Armadillo-type fold |
| Homologous_superfamily | IPR035897 | Toll/interleukin-1 receptor homology (TIR) domain superfamily |
Domain Details Per Protein
| Protein | Length | Armadillo-like helical | Armadillo-type fold | Sterile alpha and TIR motif-containing protein 1 | Sterile alpha motif domain | Sterile alpha motif/pointed domain superfamily | Toll/interleukin-1 receptor homology (TIR) domain | Toll/interleukin-1 receptor homology (TIR) domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1QWA8
|
713 |
Interactions and Pathways
No data available
Plasmids
No data available