Gene

rab5ab

ID
ZDB-GENE-040122-3
Name
RAB5A, member RAS oncogene family, b
Symbol
rab5ab Nomenclature History
Previous Names
  • rab5al
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have GTPase activity. Involved in several processes, including Spemann organizer formation; epiboly involved in gastrulation with mouth forming second; and nodal signaling pathway. Predicted to localize to axon; cytoplasmic vesicle; and plasma membrane. Orthologous to human RAB5A (RAB5A, member RAS oncogene family).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Kenyon et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rab5ab Human Ortholog
No data available
Associated With rab5ab Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005225 Small GTP-binding domain
Family IPR001806 Small GTPase
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length P-loop containing nucleoside triphosphate hydrolase Small GTPase Small GTP-binding domain
UniProtKB:Q7ZUG4 216
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA rab5ab-201 (1) Ensembl 1,279 nt
mRNA rab5ab-202 (1) Ensembl 823 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations