Gene
akt2l
- ID
- ZDB-GENE-040121-5
- Name
- v-akt murine thymoma viral oncogene homolog 2, like
- Symbol
- akt2l Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in response to peptide hormone. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytoplasm and nucleus. Is expressed in digestive system; lens; pectoral fin musculature; solid lens vesicle; and yolk syncytial layer. Human ortholog(s) of this gene implicated in glucose metabolism disease (multiple); high grade glioma; and reproductive organ cancer (multiple). Orthologous to human AKT2 (AKT serine/threonine kinase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb945 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR000961 | AGC-kinase, C-terminal |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR017892 | Protein kinase, C-terminal |
| Domain | IPR034677 | Protein Kinase B beta, catalytic domain |
| Domain | IPR039026 | Protein Kinase B, pleckstrin homology domain |
| Family | IPR014375 | Protein kinase C, alpha/beta/gamma types |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
Domain Details Per Protein
| Protein | Length | AGC-kinase, C-terminal | PH-like domain superfamily | Pleckstrin homology domain | Protein kinase, ATP binding site | Protein Kinase B beta, catalytic domain | Protein Kinase B, pleckstrin homology domain | Protein kinase C, alpha/beta/gamma types | Protein kinase, C-terminal | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9QBX9
|
625 | |||||||||||
|
UniProtKB:A0A8M9QKM2
|
400 | |||||||||||
|
UniProtKB:A0A8M9QGH5
|
347 | |||||||||||
|
UniProtKB:Q802Y3
|
478 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available