Gene

mcm3l

ID

ZDB-GENE-040121-2

Name

MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like

Symbol

mcm3l Nomenclature History

Previous Names

MCM3m (1)
empty nest (1)
etn (1)

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to have DNA replication origin binding activity and single-stranded DNA binding activity. Predicted to be involved in DNA-dependent DNA replication and double-strand break repair via break-induced replication. Predicted to localize to MCM complex and nucleus. Orthologous to human MCM3 (minichromosome maintenance complex component 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:55703 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Abrams et al., 2020
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mcm3l Human Ortholog

No data available

Associated With mcm3l Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018525	Mini-chromosome maintenance, conserved site
Domain	IPR001208	MCM domain
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR027925	MCM, N-terminal domain
Domain	IPR033762	MCM OB domain
Domain	IPR041562	MCM, AAA-lid domain
Family	IPR008046	DNA replication licensing factor Mcm3
Family	IPR031327	Mini-chromosome maintenance protein
Homologous_superfamily	IPR012340	Nucleic acid-binding, OB-fold
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase