Gene

scn4bb

ID

ZDB-GENE-031116-71

Name

sodium channel, voltage-gated, type IV, beta b

Symbol

scn4bb Nomenclature History

Previous Names

scn4b.2 (1)
sb:cb973
si:ch211-139a5.5

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to be involved in ion transport. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in long QT syndrome 10. Is expressed in cardiac ventricle; liver; nervous system; and solid lens vesicle. Orthologous to human SCN4B (sodium voltage-gated channel beta subunit 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb973 (7 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With scn4bb Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
long QT syndrome 10	Alliance	Atrial fibrillation, familial, 17	611819
long QT syndrome 10	Alliance	Long QT syndrome 10	611819

Associated With scn4bb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003599	Immunoglobulin domain subtype
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013106	Immunoglobulin V-set domain
Family	IPR000920	Myelin P0 protein-related
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily

Domain Details Per Protein

Protein	Length	Immunoglobulin domain subtype	Immunoglobulin-like domain	Immunoglobulin-like domain superfamily	Immunoglobulin-like fold	Immunoglobulin V-set domain	Myelin P0 protein-related
UniProtKB:Q06W25 InterPro	232

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	scn4bb-201 (1) Ensembl	Ensembl	1,876 nt	Select Tool ZFIN BLAST
mRNA	scn4bb-202 (1) Ensembl	Ensembl	645 nt	Select Tool
mRNA	scn4bb-203 (1) Ensembl	Ensembl	502 nt	Select Tool
mRNA	scn4bb-204 (1) Ensembl	Ensembl	1,153 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations