Gene
pfkfb4b
- ID
- ZDB-GENE-031031-4
- Name
- 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b
- Symbol
- pfkfb4b Nomenclature History
- Previous Names
-
- pfkfb4
- pfkfb4l
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have 6-phosphofructo-2-kinase activity and fructose-2,6-bisphosphate 2-phosphatase activity. Predicted to be involved in fructose 2,6-bisphosphate metabolic process. Predicted to localize to cytosol. Is expressed in central nervous system; forerunner cell group; intermediate cell mass of mesoderm; neural plate; and ventral mesoderm. Orthologous to human PFKFB4 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:64150 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR001345 | Phosphoglycerate/bisphosphoglycerate mutase, active site |
| Domain | IPR013079 | 6-phosphofructo-2-kinase |
| Family | IPR003094 | Fructose-2,6-bisphosphatase |
| Family | IPR013078 | Histidine phosphatase superfamily, clade-1 |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR029033 | Histidine phosphatase superfamily |
Domain Details Per Protein
| Protein | Length | 6-phosphofructo-2-kinase | Fructose-2,6-bisphosphatase | Histidine phosphatase superfamily | Histidine phosphatase superfamily, clade-1 | Phosphoglycerate/bisphosphoglycerate mutase, active site | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|
|
UniProtKB:F6NXI0
|
485 | ||||||
|
UniProtKB:Q7T325
|
469 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pfkfb4b-201
(1)
|
Ensembl | 2,684 nt | ||
| mRNA |
pfkfb4b-202
(1)
|
Ensembl | 2,227 nt | ||
| ncRNA |
pfkfb4b-003
(1)
|
Ensembl | 792 nt | ||
| ncRNA |
pfkfb4b-004
(1)
|
Ensembl | 456 nt |
Interactions and Pathways
No data available
Plasmids
No data available