Gene

eif4a1a

ID

ZDB-GENE-031030-2

Name

eukaryotic translation initiation factor 4A1A

Symbol

eif4a1a Nomenclature History

Previous Names

eif4a1
fb49a04
im:7143023 (1)
wu:fb20a10 (1)
wu:fb49a04 (1)
wu:fc76a02 (1)
wu:fc96c01 (1)
wu:fd15g03 (1)

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to enable translation initiation factor activity. Predicted to be involved in cytoplasmic translational initiation. Predicted to act upstream of or within translational initiation. Is expressed in several structures, including immature eye; neural rod; neuromast; paraxial mesoderm; and somite. Orthologous to human EIF4A1 (eukaryotic translation initiation factor 4A1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

14 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6909894 (1 image)
IMAGE:7143023 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With eif4a1a Human Ortholog

No data available

Associated With eif4a1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001650	Helicase, C-terminal domain-like
Domain	IPR011545	DEAD/DEAH box helicase domain
Domain	IPR014001	Helicase superfamily 1/2, ATP-binding domain
Domain	IPR014014	RNA helicase, DEAD-box type, Q motif
Domain	IPR044728	ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase

Domain Details Per Protein

Protein	Length	ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain	DEAD/DEAH box helicase domain	Helicase, C-terminal domain-like	Helicase superfamily 1/2, ATP-binding domain	P-loop containing nucleoside triphosphate hydrolase	RNA helicase, DEAD-box type, Q motif
UniProtKB:Q802C9 InterPro	406

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	eif4a1a-201 (1) Ensembl	Ensembl	2,370 nt	Select Tool ZFIN BLAST
ncRNA	eif4a1a-002 (1) Ensembl	Ensembl	1,004 nt	Select Tool ZFIN BLAST
ncRNA	eif4a1a-003 (1) Ensembl	Ensembl	677 nt	Select Tool ZFIN BLAST
ncRNA	eif4a1a-004 (1) Ensembl	Ensembl	382 nt	Select Tool ZFIN BLAST
ncRNA	eif4a1a-005 (1) Ensembl	Ensembl	883 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations