Gene
ovol1a
- ID
- ZDB-GENE-031010-37
- Name
- ovo-like zinc finger 1a
- Symbol
- ovol1a Nomenclature History
- Previous Names
-
- ovol1
- sb:cb956 (1)
- zgc:171804
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and sequence-specific DNA binding activity. Involved in establishment of protein localization to membrane; neural crest cell migration; and pigment cell development. Localizes to nucleus. Human ortholog(s) of this gene implicated in posterior polymorphous corneal dystrophy 1. Is expressed in several structures, including EVL; digestive system; periderm; prechordal plate; and sensory system. Orthologous to several human genes including OVOL1 (ovo like transcriptional repressor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb956 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Piloto et al., 2010
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Ovo-like | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|
|
UniProtKB:F8W4G4
|
319 | |||
|
UniProtKB:A9JSU5
|
256 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ovol1a-201
(1)
|
Ensembl | 2,536 nt |
Interactions and Pathways
No data available
Plasmids
No data available