Gene

vps13a

ID

ZDB-GENE-030926-1

Name

vacuolar protein sorting 13 homolog A

Symbol

vps13a Nomenclature History

Previous Names

chac (1)
wu:fc10c04

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Predicted to be involved in autophagy; protein retention in Golgi apparatus; and protein targeting to vacuole. Predicted to localize to extrinsic component of membrane. Human ortholog(s) of this gene implicated in choreaacanthocytosis and choreatic disease. Orthologous to human VPS13A (vacuolar protein sorting 13 homolog A).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Hoshijima et al., 2002

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With vps13a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
choreaacanthocytosis	Alliance	Choreoacanthocytosis	200150

Associated With vps13a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR009543	Vacuolar protein sorting-associated protein 13, VPS13 adaptor binding domain
Domain	IPR015412	Atg2/VPS13, C-terminal
Domain	IPR026854	Vacuolar protein sorting-associated protein 13-like, N-terminal domain
Domain	IPR031642	VPS13, middle RBG modules
Domain	IPR031645	Vacuolar protein sorting-associated protein 13, DH-like domain
Domain	IPR031646	Vacuolar protein sorting-associated protein 13, extended chorein
Domain	IPR049424	Intermembrane lipid transfer protein VPS13, C-terminal
Family	IPR026847	Vacuolar protein sorting-associated protein 13