Gene
fbxl3a
- ID
- ZDB-GENE-030912-5
- Name
- F-box and leucine-rich repeat protein 3a
- Symbol
- fbxl3a Nomenclature History
- Previous Names
-
- im:7153024
- zgc:103721 (1)
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to contribute to ubiquitin protein ligase activity. Predicted to be involved in several processes, including G2/M transition of mitotic cell cycle; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; and entrainment of circadian clock by photoperiod. Predicted to localize to SCF ubiquitin ligase complex; cytosol; and nucleus. Orthologous to human FBXL3 (F-box and leucine rich repeat protein 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103721 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Intellectual developmental disorder with short stature, facial anomalies, and speech defects | 606220 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | F-box domain | F-box-like domain superfamily | Leucine-rich repeat domain superfamily |
|---|---|---|---|---|
|
UniProtKB:Q7T162
|
431 | |||
|
UniProtKB:Q5XJ37
|
431 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA | fbxl3a-001 (1) | Havana | 2,325 nt | ||
| mRNA |
fbxl3a-201
(1)
|
Ensembl | 1,831 nt | ||
| mRNA |
fbxl3a-202
(1)
|
Ensembl | 1,947 nt | ||
| mRNA |
fbxl3a-203
(1)
|
Ensembl | 1,297 nt |
Interactions and Pathways
No data available
Plasmids
No data available