Gene

daam1a

ID

ZDB-GENE-030911-6

Name

dishevelled associated activator of morphogenesis 1a

Symbol

daam1a Nomenclature History

Previous Names

daam1

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to have Rho GTPase binding activity and actin binding activity. Involved in habenula development and pronephros development. Predicted to localize to stress fiber. Is expressed in brain and dorsal habenular nucleus. Orthologous to human DAAM1 (dishevelled associated activator of morphogenesis 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Colombo et al., 2013

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 6 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With daam1a Human Ortholog

No data available

Associated With daam1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR010472	Formin, FH3 domain
Domain	IPR010473	Formin, GTPase-binding domain
Domain	IPR014767	Diaphanous autoregulatory (DAD) domain
Domain	IPR014768	Rho GTPase-binding/formin homology 3 (GBD/FH3) domain
Domain	IPR015425	Formin, FH2 domain
Family	IPR051425	Formin Homology
Homologous_superfamily	IPR011989	Armadillo-like helical
Homologous_superfamily	IPR016024	Armadillo-type fold
Homologous_superfamily	IPR042201	Formin, FH2 domain superfamily

Domain Details Per Protein

Protein	Length	Armadillo-like helical	Armadillo-type fold	Diaphanous autoregulatory (DAD) domain	Formin, FH2 domain	Formin, FH2 domain superfamily	Formin, FH3 domain	Formin, GTPase-binding domain	Formin Homology	Rho GTPase-binding/formin homology 3 (GBD/FH3) domain
UniProtKB:A0A0R4IER9 InterPro	1060
UniProtKB:A0A8M6Z2D8 InterPro	1069

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	daam1a-201 (1) Ensembl	Ensembl	3,799 nt	Select Tool ZFIN BLAST
mRNA	daam1a-202 (1) Ensembl	Ensembl	605 nt	Select Tool ZFIN BLAST
mRNA	daam1a-203 (1) Ensembl	Ensembl	5,603 nt	Select Tool ZFIN BLAST
mRNA	daam1a-204 (1) Ensembl	Ensembl	4,789 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations