Gene

drd2l

ID
ZDB-GENE-030910-1
Name
dopamine receptor D2 like
Symbol
drd2l Nomenclature History
Previous Names
  • drd2b (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to enable G protein-coupled receptor activity and dopamine neurotransmitter receptor activity, coupled via Gi/Go. Predicted to be involved in G protein-coupled receptor signaling pathway; negative regulation of cytosolic calcium ion concentration; and negative regulation of glutamatergic synaptic transmission. Predicted to act upstream of or within dopamine receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in glutamatergic synapse and presynaptic membrane. Is expressed in brain and spinal cord.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Liu et al., 2006
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With drd2l Human Ortholog
No data available
Associated With drd2l Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR000929 Dopamine receptor family
Family IPR001922 Dopamine D2 receptor
Domain Details Per Protein
Protein Length Dopamine D2 receptor Dopamine receptor family GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like
UniProtKB:Q7T1A2 437
UniProtKB:X1WBR1 450
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA drd2l-201 (1) Ensembl 1,327 nt
mRNA drd2l-202 (1) Ensembl 1,535 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations