Gene
hs6st2
- ID
- ZDB-GENE-030909-14
- Name
- heparan sulfate 6-O-sulfotransferase 2
- Symbol
- hs6st2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Exhibits heparan sulfate 6-O-sulfotransferase activity. Involved in branching involved in blood vessel morphogenesis and embryonic eye morphogenesis. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability. Is expressed in several structures, including immature eye; nervous system; neural keel; somite; and tail bud. Orthologous to human HS6ST2 (heparan sulfate 6-O-sulfotransferase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Paganini-Miozzo syndrome | Alliance | ?Paganini-Miozzo syndrome | 301025 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Heparan sulphate 6-sulfotransferase/Protein-tyrosine sulfotransferase | P-loop containing nucleoside triphosphate hydrolase | Sulfotransferase |
|---|---|---|---|---|
|
UniProtKB:Q800H9
|
468 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
hs6st2-201
(1)
|
Ensembl | 2,476 nt |
Interactions and Pathways
No data available
Plasmids
No data available