Gene
nr1i2
- ID
- ZDB-GENE-030903-3
- Name
- nuclear receptor subfamily 1, group I, member 2
- Symbol
- nr1i2 Nomenclature History
- Previous Names
-
- PXR (1)
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Exhibits nuclear receptor activity and steroid hormone receptor activity. Involved in regulation of transcription, DNA-templated; response to toxic substance; and transcription by RNA polymerase II. Predicted to localize to RNA polymerase II transcription factor complex. Is expressed in several structures, including adenohypophyseal placode; brain; heart; liver; and pleuroperitoneal region. Orthologous to human NR1I2 (nuclear receptor subfamily 1 group I member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 21 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- af502918 (24 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Hu et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000536 | Nuclear hormone receptor, ligand-binding domain |
| Domain | IPR001628 | Zinc finger, nuclear hormone receptor-type |
| Family | IPR001723 | Nuclear hormone receptor |
| Family | IPR050234 | Nuclear hormone receptor family NR1 subfamily |
| Homologous_superfamily | IPR013088 | Zinc finger, NHR/GATA-type |
| Homologous_superfamily | IPR035500 | Nuclear hormone receptor-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Nuclear hormone receptor | Nuclear hormone receptor family NR1 subfamily | Nuclear hormone receptor, ligand-binding domain | Nuclear hormone receptor-like domain superfamily | Zinc finger, NHR/GATA-type | Zinc finger, nuclear hormone receptor-type |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9QAV5
|
417 | ||||||
|
UniProtKB:A5WYG8
|
430 | ||||||
|
UniProtKB:B0V1H8
|
430 |
Interactions and Pathways
No data available
Plasmids
No data available