Gene
tpbg1b
- ID
- ZDB-GENE-030827-4
- Name
- trophoblast glycoprotein 1b
- Symbol
- tpbg1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Involved in convergent extension involved in axis elongation and regulation of Wnt signaling pathway. Localizes to plasma membrane. Is expressed in several structures, including anterior neural keel; forebrain midbrain boundary neural rod; margin; nervous system; and neural plate. Orthologous to human TPBG (trophoblast glycoprotein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb613 (23 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Kagermeier-Schenk et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000372 | Leucine-rich repeat N-terminal domain |
| Domain | IPR000483 | Cysteine-rich flanking region, C-terminal |
| Family | IPR052286 | Wnt/beta-catenin signaling inhibitor |
| Homologous_superfamily | IPR032675 | Leucine-rich repeat domain superfamily |
| Repeat | IPR001611 | Leucine-rich repeat |
| Repeat | IPR003591 | Leucine-rich repeat, typical subtype |
Domain Details Per Protein
| Protein | Length | Cysteine-rich flanking region, C-terminal | Leucine-rich repeat | Leucine-rich repeat domain superfamily | Leucine-rich repeat N-terminal domain | Leucine-rich repeat, typical subtype | Wnt/beta-catenin signaling inhibitor |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A0R4ITS3
|
372 |
Interactions and Pathways
No data available
Plasmids
No data available