Gene
birc2
- ID
- ZDB-GENE-030825-6
- Name
- baculoviral IAP repeat containing 2
- Symbol
- birc2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have cysteine-type endopeptidase inhibitor activity involved in apoptotic process and ubiquitin protein ligase activity. Predicted to be involved in inhibition of cysteine-type endopeptidase activity involved in apoptotic process and positive regulation of protein ubiquitination. Predicted to localize to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in breast cancer. Is expressed in dorsal aorta; intersegmental vessel; and posterior cardinal vein. Orthologous to several human genes including BIRC2 (baculoviral IAP repeat containing 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6903716 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001315 | CARD domain |
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR041933 | BIRC2/BIRC3, UBA domain |
| Domain | IPR048875 | BIRC2/3-like, UBA domain |
| Family | IPR050784 | Inhibitor of Apoptosis |
| Homologous_superfamily | IPR011029 | Death-like domain superfamily |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Repeat | IPR001370 | BIR repeat |
Domain Details Per Protein
| Protein | Length | BIRC2/3-like, UBA domain | BIRC2/BIRC3, UBA domain | BIR repeat | CARD domain | Death-like domain superfamily | Inhibitor of Apoptosis | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A2R8QDZ3
|
633 | ||||||||
|
UniProtKB:Q7T0K2
|
647 | ||||||||
|
UniProtKB:Q8UWD2
|
628 |
Interactions and Pathways
No data available
Plasmids
No data available