Gene
slit1b
- ID
- ZDB-GENE-030722-4
- Name
- slit homolog 1b (Drosophila)
- Symbol
- slit1b Nomenclature History
- Previous Names
-
- chunp9742
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to have calcium ion binding activity. Involved in cranial nerve morphogenesis. Is expressed in central nervous system; forebrain; hindbrain; hindbrain nucleus; and retinal inner nuclear layer. Orthologous to human SLIT1 (slit guidance ligand 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Zecca et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR013032 | EGF-like, conserved site |
| Conserved_site | IPR018097 | EGF-like calcium-binding, conserved site |
| Domain | IPR000372 | Leucine-rich repeat N-terminal domain |
| Domain | IPR000483 | Cysteine-rich flanking region, C-terminal |
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR001791 | Laminin G domain |
| Domain | IPR001881 | EGF-like calcium-binding domain |
| Domain | IPR006207 | Cystine knot, C-terminal |
| Family | IPR051355 | Notch and Slit guidance protein |
| Homologous_superfamily | IPR009030 | Growth factor receptor cysteine-rich domain superfamily |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| Homologous_superfamily | IPR032675 | Leucine-rich repeat domain superfamily |
| PTM | IPR000152 | EGF-type aspartate/asparagine hydroxylation site |
| Repeat | IPR001611 | Leucine-rich repeat |
| Repeat | IPR003591 | Leucine-rich repeat, typical subtype |
Domain Details Per Protein
| Protein | Length | Concanavalin A-like lectin/glucanase domain superfamily | Cysteine-rich flanking region, C-terminal | Cystine knot, C-terminal | EGF-like calcium-binding, conserved site | EGF-like calcium-binding domain | EGF-like, conserved site | EGF-like domain | EGF-type aspartate/asparagine hydroxylation site | Growth factor receptor cysteine-rich domain superfamily | Laminin G domain | Leucine-rich repeat | Leucine-rich repeat domain superfamily | Leucine-rich repeat N-terminal domain | Leucine-rich repeat, typical subtype | Notch and Slit guidance protein |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q3Y6S4
|
1532 | |||||||||||||||
|
UniProtKB:A0A0R4IU60
|
1531 | |||||||||||||||
|
UniProtKB:A0A8M9PRT4
|
1241 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slit1b-201
(1)
|
Ensembl | 2,468 nt | ||
| mRNA |
slit1b-202
(1)
|
Ensembl | 1,919 nt | ||
| mRNA |
slit1b-203
(1)
|
Ensembl | 4,839 nt | ||
| mRNA |
slit1b-204
(1)
|
Ensembl | 5,117 nt |
Interactions and Pathways
No data available
Plasmids