Gene
fgf10a
- ID
- ZDB-GENE-030715-1
- Name
- fibroblast growth factor 10a
- Symbol
- fgf10a Nomenclature History
- Previous Names
-
- fgf10
- dae
- daedalus
- wu:fd11d03 (1)
- zgc:109774
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have fibroblast growth factor receptor binding activity and growth factor activity. Involved in several processes, including embryonic pectoral fin morphogenesis; hard palate development; and posterior lateral line development. Predicted to localize to extracellular region. Human ortholog(s) of this gene implicated in LADD syndrome and aplasia of lacrimal and salivary glands. Is expressed in several structures, including ectoderm; fin bud; gut; head; and lateral line system. Orthologous to human FGF10 (fibroblast growth factor 10).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 97 figures from 59 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:109774 (13 images)
- eu110 (19 images)
Wild Type Expression Summary
- All Phenotype Data
- 17 figures from 11 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| aplasia of lacrimal and salivary glands | Alliance | Aplasia of lacrimal and salivary glands | 180920 |
| lacrimoauriculodentodigital syndrome 3 | Alliance | LADD syndrome 3 | 620193 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytokine IL1/FGF | Fibroblast growth factor family |
|---|---|---|---|
|
UniProtKB:Q8AY90
|
201 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
fgf10a-201
(1)
|
Ensembl | 2,005 nt | ||
| mRNA |
fgf10a-202
(1)
|
Ensembl | 2,383 nt |
Interactions and Pathways
No data available
Plasmids
No data available