Gene

cntfr

ID

ZDB-GENE-030616-82

Name

ciliary neurotrophic factor receptor

Symbol

cntfr Nomenclature History

Previous Names

cb549 (1)
fj33e02
sb:cb549
si:bz76a6.1
si:dz248f2.1
si:rp71-76a6.1
wu:fj33e02

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to have cytokine binding activity and cytokine receptor activity. Involved in positive regulation of axon regeneration. Predicted to localize to external side of plasma membrane and receptor complex. Is expressed in several structures, including central nervous system; cranial ganglion; hindbrain neural plate; immature eye; and pectoral fin musculature. Orthologous to human CNTFR (ciliary neurotrophic factor receptor).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb549 (16 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cntfr Human Ortholog

No data available

Associated With cntfr Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR003530	Long hematopoietin receptor, soluble alpha chain, conserved site
Domain	IPR003961	Fibronectin type III
Domain	IPR007110	Immunoglobulin-like domain
Family	IPR050379	Type I Cytokine Receptor
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036116	Fibronectin type III superfamily
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily