Gene

g2e3

ID

ZDB-GENE-030616-400

Name

G2/M-phase specific E3 ubiquitin protein ligase

Symbol

g2e3 Nomenclature History

Previous Names

sb:cb726 (1)
si:busm1-234g15.1
si:dz234g15.1
wu:fe02a06 (1)
wu:fe24c12 (1)

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to have metal ion binding activity and ubiquitin-protein transferase activity. Is expressed in central nervous system; head; pectoral fin musculature; and proliferative region. Orthologous to human G2E3 (G2/M-phase specific E3 ubiquitin protein ligase).

Genome Resources

Note

novel protein similar to KIAA1333

Comparative Information

Expression

All Expression Data

7 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb726 (7 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With g2e3 Human Ortholog

No data available

Associated With g2e3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019786	Zinc finger, PHD-type, conserved site
Domain	IPR000569	HECT domain
Domain	IPR001965	Zinc finger, PHD-type
Domain	IPR034732	Extended PHD (ePHD) domain
Domain	IPR042012	PHF7/G2E3, PHD domain
Domain	IPR042013	PHF7/G2E3, ePHD domain
Family	IPR051188	PHD-type Zinc Finger Domain-Containing Protein
Homologous_superfamily	IPR011011	Zinc finger, FYVE/PHD-type
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily	IPR035983	HECT, E3 ligase catalytic domain