Gene
ccdc65
- ID
- ZDB-GENE-030616-358
- Name
- coiled-coil domain containing 65
- Symbol
- ccdc65 Nomenclature History
- Previous Names
-
- si:busm1-202l16.3 (1)
- si:dz202l16.3
- zgc:92302
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Acts upstream of or within regulation of cilium movement. Predicted to be located in cytoplasm; cytoskeleton; and motile cilium. Predicted to be part of axonemal dynein complex. Predicted to be active in axoneme. Is expressed in pronephric duct and spinal cord. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 27. Orthologous to human CCDC65 (coiled-coil domain containing 65).
- Genome Resources
- Note
-
novel protein similar to human NYD-SP28
- Comparative Information
-
- All Expression Data
- 1 figure from Austin-Tse et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary ciliary dyskinesia 27 | Alliance | Ciliary dyskinesia, primary, 27 | 615504 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Dynein regulatory complex protein | Dynein regulatory complex protein 1/2, N-terminal |
|---|---|---|---|
|
UniProtKB:Q6DHI2
|
492 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ccdc65-201
(1)
|
Ensembl | 1,531 nt | ||
| mRNA | ottdart00000001492 (1) | Havana | 1,344 nt |
Interactions and Pathways
No data available
Plasmids
No data available