Gene

tnnt3b

ID

ZDB-GENE-030520-2

Name

troponin T type 3b (skeletal, fast)

Symbol

tnnt3b Nomenclature History

Previous Names

cb44 (1)
sb:cb44 (1)

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to contribute to calcium-dependent ATPase activity and tropomyosin binding activity. Involved in sarcomere organization. Predicted to localize to troponin complex. Human ortholog(s) of this gene implicated in distal arthrogryposis type 2B and distal arthrogryposis type 2B2. Is expressed in musculature system and somite. Orthologous to human TNNT3 (troponin T3, fast skeletal type).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

16 figures from 8 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb44 (4 images)
IMAGE:7145902 (12 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Ferrante et al., 2011
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tnnt3b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
distal arthrogryposis type 2B2	Alliance	Arthrogryposis, distal, type 2B2	618435

Associated With tnnt3b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR001978	Troponin
Family	IPR027707	Troponin T
Homologous_superfamily	IPR038077	Troponin domain superfamily

Domain Details Per Protein

Protein	Length	Troponin	Troponin domain superfamily	Troponin T
UniProtKB:F1Q5F2 InterPro
UniProtKB:A8WGA6 InterPro	284
UniProtKB:Q7ZZW4 InterPro	232

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	tnnt3b-201 (1) Ensembl	Ensembl	855 nt	Select Tool ZFIN BLAST
mRNA	tnnt3b-202 (1) Ensembl	Ensembl	687 nt	Select Tool ZFIN BLAST
mRNA	tnnt3b-203 (1) Ensembl	Ensembl	1,050 nt	Select Tool ZFIN BLAST
mRNA	tnnt3b-204 (1) Ensembl	Ensembl	1,068 nt	Select Tool ZFIN BLAST
mRNA	tnnt3b-206 (1) Ensembl	Ensembl	1,061 nt	Select Tool ZFIN BLAST
mRNA	tnnt3b-207 (1) Ensembl	Ensembl	1,224 nt	Select Tool ZFIN BLAST
mRNA	tnnt3b-208 (1) Ensembl	Ensembl	822 nt	Select Tool ZFIN BLAST
mRNA	tnnt3b-209 (1) Ensembl	Ensembl	771 nt	Select Tool ZFIN BLAST
mRNA	tnnt3b-210 (1) Ensembl	Ensembl	727 nt	Select Tool ZFIN BLAST
mRNA	tnnt3b-212 (1) Ensembl	Ensembl	829 nt	Select Tool ZFIN BLAST
mRNA	tnnt3b-213 (1) Ensembl	Ensembl	479 nt	Select Tool ZFIN BLAST
mRNA	tnnt3b-214 (1) Ensembl	Ensembl	754 nt	Select Tool ZFIN BLAST
mRNA	tnnt3b-215 (1) Ensembl	Ensembl	885 nt	Select Tool ZFIN BLAST
ncRNA	tnnt3b-007 (1) Ensembl	Ensembl	831 nt	Select Tool ZFIN BLAST
ncRNA	tnnt3b-013 (1) Ensembl	Ensembl	750 nt	Select Tool ZFIN BLAST
ncRNA	tnnt3b-014 (1) Ensembl	Ensembl	398 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations