Gene

slc16a1b

ID

ZDB-GENE-030515-5

Name

solute carrier family 16 member 1b

Symbol

slc16a1b Nomenclature History

Previous Names

cb517 (1)
MCT1 (1)
slc16a1

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Predicted to act upstream of or within transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including central nervous system; digestive system; liver primordium; musculature system; and neural tube. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 7. Orthologous to human SLC16A1 (solute carrier family 16 member 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

13 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb517 (22 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With slc16a1b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
familial hyperinsulinemic hypoglycemia 7	Alliance	Hyperinsulinemic hypoglycemia, familial, 7	610021
		Erythrocyte lactate transporter defect	245340
		Monocarboxylate transporter 1 deficiency	616095

Associated With slc16a1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR020846	Major facilitator superfamily domain
Family	IPR004743	Monocarboxylate transporter
Family	IPR011701	Major facilitator superfamily
Family	IPR050327	Proton-linked Monocarboxylate Transporter
Homologous_superfamily	IPR036259	MFS transporter superfamily