Gene
tshba
- ID
- ZDB-GENE-030513-3
- Name
- thyroid stimulating hormone subunit beta a
- Symbol
- tshba Nomenclature History
- Previous Names
-
- tshb (1)
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to contribute to hormone activity. Predicted to be involved in G protein-coupled receptor signaling pathway and hormone-mediated signaling pathway. Predicted to localize to cytoplasm and extracellular space. Human ortholog(s) of this gene implicated in congenital nongoitrous hypothyroidism 4 and hypothyroidism. Is expressed in adenohypophyseal placode; head; and hypophysis. Orthologous to human TSHB (thyroid stimulating hormone subunit beta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 48 figures from 34 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 7 figures from Song et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital nongoitrous hypothyroidism 4 | Alliance | Hypothyroidism, congenital, nongoitrous 4 | 275100 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cystine-knot cytokine | Glycoprotein hormone subunit beta | Gonadotropin, beta subunit | Gonadotropin, beta subunit, conserved site |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PZI4
|
129 | ||||
|
UniProtKB:Q801K4
|
148 | ||||
|
UniProtKB:A0A8M9PLW7
|
182 |
Interactions and Pathways
No data available
Plasmids
No data available