Gene

mc3r

ID
ZDB-GENE-030502-3
Name
melanocortin 3 receptor
Symbol
mc3r Nomenclature History
Previous Names
  • zgc:194235
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have melanocortin receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to localize to integral component of membrane and plasma membrane. Human ortholog(s) of this gene implicated in obesity. Is expressed in brain and epiphysis. Orthologous to human MC3R (melanocortin 3 receptor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Renquist et al., 2013
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mc3r Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Obesity, severe, susceptibility to, BMIQ9} 602025
Associated With mc3r Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR001671 Melanocortin/ACTH receptor
Family IPR001908 Melanocortin receptor 3-5
Family IPR002122 Melanocortin 3 receptor
Domain Details Per Protein
Protein Length GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like Melanocortin 3 receptor Melanocortin/ACTH receptor Melanocortin receptor 3-5
UniProtKB:F1QQG9 327
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA mc3r-201 (1) Ensembl 1,050 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations