Gene

sephs3

ID

ZDB-GENE-030327-5

Name

selenophosphate synthetase 3

Symbol

sephs3 Nomenclature History

Previous Names

sephs2
sps2
cb701 (1)
zgc:92096

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to enable selenide, water dikinase activity. Predicted to be involved in selenocysteine biosynthetic process. Predicted to act upstream of or within phosphorylation. Predicted to be active in cytoplasm. Is expressed in several structures, including brain; digestive system; immature eye; pronephros; and sensory system. Orthologous to human SEPHS2 (selenophosphate synthetase 2).

Genome Resources

Note

updated to sephs3 because it has been demonstrated that this gene is not a true ortholog to mammalian (placental) SEPHS2.

Comparative Information

Expression

All Expression Data

11 figures from 5 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb701 (12 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sephs3 Human Ortholog

No data available

Associated With sephs3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR010918	PurM-like, C-terminal domain
Domain	IPR016188	PurM-like, N-terminal domain
Family	IPR004536	Selenophosphate synthetase
Homologous_superfamily	IPR036676	PurM-like, C-terminal domain superfamily
Homologous_superfamily	IPR036921	PurM-like, N-terminal domain superfamily