Gene

gli1

ID
ZDB-GENE-030321-1
Name
GLI family zinc finger 1
Symbol
gli1 Nomenclature History
Previous Names
  • detour
  • dtr
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in several processes, including muscle cell fate specification; nervous system development; and positive regulation of smoothened signaling pathway. Localizes to Hedgehog signaling complex. Is expressed in several structures, including central nervous system; head; neural plate; neural tube; and paraxial mesoderm. Orthologous to human GLI1 (GLI family zinc finger 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
57 figures from 45 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
30 figures from 14 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gli1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
preaxial polydactyly I Alliance Polydactyly, preaxial I 174400
Polydactyly, postaxial, type A8 618123
Associated With gli1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013087 Zinc finger C2H2-type
Family IPR043359 C2H2-type zinc-finger protein GLI-like
Homologous_superfamily IPR036236 Zinc finger C2H2 superfamily
Domain Details Per Protein
Protein Length C2H2-type zinc-finger protein GLI-like Zinc finger C2H2 superfamily Zinc finger C2H2-type
UniProtKB:Q800Z9 1404
UniProtKB:F1QAC4 1404
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA gli1-201 (1) Ensembl 7,333 nt
Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations