Gene

p2rx1

ID
ZDB-GENE-030319-1
Name
purinergic receptor P2X, ligand-gated ion channel, 1
Symbol
p2rx1 Nomenclature History
Previous Names
  • zP2X1_tv1 (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Exhibits extracellularly ATP-gated cation channel activity. Predicted to be involved in cation transmembrane transport and response to ATP. Predicted to localize to integral component of nuclear inner membrane. Is expressed in hypothalamus and midbrain. Orthologous to human P2RX1 (purinergic receptor P2X 1).
Genome Resources
Note
The AAQ21194 sequence was non-functional because of a substitution of serine 239 with a tyrosine as shown in ZDB-PUB-081022-21
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With p2rx1 Human Ortholog
No data available
Associated With p2rx1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR053792 ATP P2X receptor, conserved site
Family IPR001429 P2X purinoreceptor
Family IPR003044 P2X1 purinoceptor
Homologous_superfamily IPR027309 P2X purinoreceptor extracellular domain superfamily
Domain Details Per Protein
Protein Length ATP P2X receptor, conserved site P2X1 purinoceptor P2X purinoreceptor P2X purinoreceptor extracellular domain superfamily
UniProtKB:Q7SZM0 398
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA p2rx1-201 (1) Ensembl 4,499 nt
mRNA p2rx1-202 (1) Ensembl 1,384 nt
mRNA p2rx1-203 (1) Ensembl 4,617 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations