Gene
usp10
- ID
- ZDB-GENE-030219-132
- Name
- ubiquitin specific peptidase 10
- Symbol
- usp10 Nomenclature History
- Previous Names
-
- id:ibd1190
- wu:fc19h08
- wu:fc76g05
- wu:fi11g01
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in DNA damage response, signal transduction by p53 class mediator; regulation of autophagy; and regulation of protein stability. Predicted to act upstream of or within protein deubiquitination and proteolysis. Predicted to be active in cytosol and nucleus. Is expressed in immature eye and optic tectum. Orthologous to human USP10 (ubiquitin specific peptidase 10).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Tse et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018200 | Ubiquitin specific protease, conserved site |
| Domain | IPR001394 | Peptidase C19, ubiquitin carboxyl-terminal hydrolase |
| Domain | IPR028889 | Ubiquitin specific protease domain |
| Family | IPR050164 | Ubiquitin carboxyl-terminal hydrolases |
| Homologous_superfamily | IPR038765 | Papain-like cysteine peptidase superfamily |
Domain Details Per Protein
| Protein | Length | Papain-like cysteine peptidase superfamily | Peptidase C19, ubiquitin carboxyl-terminal hydrolase | Ubiquitin carboxyl-terminal hydrolases | Ubiquitin specific protease, conserved site | Ubiquitin specific protease domain |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2BGE9
|
864 | |||||
|
UniProtKB:A0A0R4IVE2
|
865 | |||||
|
UniProtKB:A0A8M2BGF3
|
845 |
Interactions and Pathways
No data available
Plasmids
No data available