Gene
quo
- ID
- ZDB-GENE-030131-9944
- Name
- quattro
- Symbol
- quo Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have Rho guanyl-nucleotide exchange factor activity. Involved in animal organ morphogenesis and mesoderm morphogenesis. Is expressed in several structures, including Kupffer's vesicle; anterior axial hypoblast; forerunner cell group; mesoderm; and nervous system. Orthologous to human KIAA1755 (KIAA1755).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb9 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000219 | Dbl homology (DH) domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Family | IPR052231 | Rho GEF and signaling-related domain-containing protein |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR035899 | Dbl homology (DH) domain superfamily |
Domain Details Per Protein
| Protein | Length | Dbl homology (DH) domain | Dbl homology (DH) domain superfamily | PH-like domain superfamily | Pleckstrin homology domain | Rho GEF and signaling-related domain-containing protein |
|---|---|---|---|---|---|---|
|
UniProtKB:Q6DN89
|
1989 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance
- Gene Tree
- Ensembl
- Note
- Woods, et al. (2005. Genome Res. 15:1307-1314.) report this gene to be the ortholog of human PLEKHG4 based on amino acid similarity. Subsequent analysis suggests it is the ortholog of human KIAA1755 and mouse D630003M21Rik based on amino acid similarity and conserved synteny.