Gene

esrp2

ID

ZDB-GENE-030131-9824

Name

epithelial splicing regulatory protein 2

Symbol

esrp2 Nomenclature History

Previous Names

cb404 (1)
rbm35b
sb:cb404
zgc:77254 (1)

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to enable mRNA binding activity. Acts upstream of or within cranial skeletal system development and hard palate morphogenesis. Predicted to be located in nucleus. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nucleoplasm. Is expressed in several structures, including EVL; anterior axial hypoblast; digestive system; neurogenic placode; and pleuroperitoneal region. Orthologous to human ESRP2 (epithelial splicing regulatory protein 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb404 (12 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Burguera et al., 2017
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With esrp2 Human Ortholog

No data available

Associated With esrp2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Family	IPR050666	Epithelial Splicing Regulatory
Homologous_superfamily	IPR012337	Ribonuclease H-like superfamily
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily
Homologous_superfamily	IPR036397	Ribonuclease H superfamily

Domain Details Per Protein

Protein	Length	Epithelial Splicing Regulatory	Nucleotide-binding alpha-beta plait domain superfamily	Ribonuclease H-like superfamily	Ribonuclease H superfamily	RNA-binding domain superfamily	RNA recognition motif domain
UniProtKB:A0A8M9QH61 InterPro	576
UniProtKB:A0A8M2BGB5 InterPro	735
UniProtKB:Q7ZVR8 InterPro	736
UniProtKB:G1K2P5 InterPro	711
UniProtKB:A0A8M6Z7Q3 InterPro	687

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	esrp2-204 (1) Ensembl	Ensembl	742 nt	Select Tool ZFIN BLAST
mRNA	esrp2-201 (1) Ensembl	Ensembl	3,364 nt	Select Tool ZFIN BLAST
mRNA	esrp2-202 (1) Ensembl	Ensembl	3,435 nt	Select Tool ZFIN BLAST
mRNA	esrp2-203 (1) Ensembl	Ensembl	804 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations