Gene

ogt.1

ID

ZDB-GENE-030131-9631

Name

O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1

Symbol

ogt.1 Nomenclature History

Previous Names

ogt
ogta (1)
copy I (1)
fm81g08
wu:fc12b01
wu:fm81g08

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Enables protein N-acetylglucosaminyltransferase activity. Acts upstream of or within protein O-linked glycosylation. Is expressed in brain; caudal fin; and trunk. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 106. Orthologous to human OGT (O-linked N-acetylglucosamine (GlcNAc) transferase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Webster et al., 2009
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ogt.1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
non-syndromic X-linked intellectual disability 106	Alliance	Intellectual developmental disorder, X-linked 106	300997

Associated With ogt.1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR029489	O-GlcNAc transferase, C-terminal
Family	IPR037919	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit
Homologous_superfamily	IPR011990	Tetratricopeptide-like helical domain superfamily
Repeat	IPR019734	Tetratricopeptide repeat

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A0R4IVJ0	InterPro	1102
UniProtKB:A0A8M3B8G4	InterPro	886
UniProtKB:Q5GA11	InterPro	1046
UniProtKB:Q5GA12	InterPro	1052
UniProtKB:Q5GA13	InterPro	1062
UniProtKB:Q5GA10	InterPro	1036

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ogt.1-207 (1) Ensembl	Ensembl	498 nt	Select Tool ZFIN BLAST
mRNA	ogt.1-208 (1) Ensembl	Ensembl	3,189 nt	Select Tool ZFIN BLAST
mRNA	ogt.1-210 (1) Ensembl	Ensembl	6,832 nt	Select Tool ZFIN BLAST
mRNA	ogt.1-212 (1) Ensembl	Ensembl	4,195 nt	Select Tool ZFIN BLAST
mRNA	ogt.1-213 (1) Ensembl	Ensembl	3,159 nt	Select Tool ZFIN BLAST
mRNA	ogt.1-214 (1) Ensembl	Ensembl	431 nt	Select Tool ZFIN BLAST
mRNA	ogt.1-215 (1) Ensembl	Ensembl	7,999 nt	Select Tool ZFIN BLAST
mRNA	ogt.1-216 (1) Ensembl	Ensembl	8,047 nt	Select Tool ZFIN BLAST
ncRNA	ogt.1-005 (1) Ensembl	Ensembl	1,013 nt	Select Tool ZFIN BLAST
ncRNA	ogt.1-006 (1) Ensembl	Ensembl	744 nt	Select Tool ZFIN BLAST
ncRNA	ogt.1-007 (1) Ensembl	Ensembl	967 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations