Gene
eif2b4
- ID
- ZDB-GENE-030131-955
- Name
- eukaryotic translation initiation factor 2B, subunit 4 delta
- Symbol
- eif2b4 Nomenclature History
- Previous Names
-
- si:ch211-101l18.4
- wu:fb54a09 (1)
- zgc:110790
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have translation initiation factor activity. Predicted to be involved in translational initiation. Human ortholog(s) of this gene implicated in leukoencephalopathy with vanishing white matter. Orthologous to human EIF2B4 (eukaryotic translation initiation factor 2B subunit delta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110790 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| leukoencephalopathy with vanishing white matter 4 | Alliance | Leukoencephalopathy with vanishing white matter 4, with or without ovarian failure | 620314 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Initiation factor 2B-like, C-terminal | Initiation factor 2B-related | NagB/RpiA transferase-like |
|---|---|---|---|---|
|
UniProtKB:A0A8M2B7A3
|
541 | |||
|
UniProtKB:Q5RIE1
|
540 | |||
|
UniProtKB:A0A8M2B7A1
|
555 | |||
|
UniProtKB:A0A286Y8J6
|
554 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
eif2b4-201
(1)
|
Ensembl | 2,120 nt | ||
| mRNA |
eif2b4-203
(1)
|
Ensembl | 578 nt | ||
| mRNA |
eif2b4-205
(1)
|
Ensembl | 6,263 nt | ||
| ncRNA |
eif2b4-002
(1)
|
Ensembl | 794 nt | ||
| ncRNA |
eif2b4-004
(1)
|
Ensembl | 639 nt |
Interactions and Pathways
No data available
Plasmids
No data available