Gene
ddx5
- ID
- ZDB-GENE-030131-925
- Name
- DEAD (Asp-Glu-Ala-Asp) box helicase 5
- Symbol
- ddx5 Nomenclature History
- Previous Names
-
- wu:fa56a07
- wu:fb11e01
- wu:fb16c10
- wu:fb53b05
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Enables mRNA 3'-UTR binding activity. Acts upstream of or within oocyte maturation. Predicted to be located in membrane. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nucleus. Is expressed in gonad; immature gonad; oocyte stage I; oocyte stage II; and testis. Orthologous to human DDX5 (DEAD-box helicase 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6897305 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 7 figures from Sone et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR000629 | ATP-dependent RNA helicase DEAD-box, conserved site |
| Domain | IPR001650 | Helicase, C-terminal domain-like |
| Domain | IPR011545 | DEAD/DEAH box helicase domain |
| Domain | IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
| Domain | IPR014014 | RNA helicase, DEAD-box type, Q motif |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Length | ATP-dependent RNA helicase DEAD-box, conserved site | DEAD/DEAH box helicase domain | Helicase, C-terminal domain-like | Helicase superfamily 1/2, ATP-binding domain | P-loop containing nucleoside triphosphate hydrolase | RNA helicase, DEAD-box type, Q motif |
|---|---|---|---|---|---|---|---|
|
UniProtKB:F1Q5L6
|
617 | ||||||
|
UniProtKB:Q6NWH7
|
496 |
Interactions and Pathways
No data available
Plasmids
No data available