Gene

sulf1

ID

ZDB-GENE-030131-9242

Name

sulfatase 1

Symbol

sulf1 Nomenclature History

Previous Names

wu:fk14e08

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Description

Predicted to have N-acetylglucosamine-6-sulfatase activity and glycosaminoglycan binding activity. Involved in several processes, including neuromast deposition; regionalization; and vasculogenesis. Predicted to localize to cell surface; endoplasmic reticulum; and plasma membrane. Is expressed in several structures, including cardiovascular system; central nervous system; head; hypochord; and somite. Orthologous to human SULF1 (sulfatase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 6 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 23 figures from 4 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sulf1 Human Ortholog

No data available

Associated With sulf1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR024607	Sulfatase, conserved site
Domain	IPR000917	Sulfatase, N-terminal
Domain	IPR024609	Extracellular sulfatase, C-terminal
Homologous_superfamily	IPR017850	Alkaline-phosphatase-like, core domain superfamily

Domain Details Per Protein

Protein	Length	Alkaline-phosphatase-like, core domain superfamily	Extracellular sulfatase, C-terminal	Sulfatase, conserved site	Sulfatase, N-terminal
UniProtKB:Q6EFA1 InterPro	1099

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	sulf1-201 (1) Ensembl	Ensembl	5,991 nt	Select Tool ZFIN BLAST
mRNA	sulf1-202 (1) Ensembl	Ensembl	6,069 nt	Select Tool ZFIN BLAST
mRNA	sulf1-203 (1) Ensembl	Ensembl	4,584 nt	Select Tool
mRNA	sulf1-205 (1) Ensembl	Ensembl	887 nt	Select Tool
mRNA	sulf1-206 (1) Ensembl	Ensembl	2,625 nt	Select Tool
mRNA	sulf1-207 (1) Ensembl	Ensembl	2,679 nt	Select Tool
mRNA	sulf1-208 (1) Ensembl	Ensembl	6,188 nt	Select Tool ZFIN BLAST
mRNA	sulf1-209 (1) Ensembl	Ensembl	6,276 nt	Select Tool ZFIN BLAST
mRNA	sulf1-210 (1) Ensembl	Ensembl	5,994 nt	Select Tool ZFIN BLAST
mRNA	sulf1-211 (1) Ensembl	Ensembl	6,222 nt	Select Tool ZFIN BLAST
mRNA	sulf1-212 (1) Ensembl	Ensembl	5,672 nt	Select Tool ZFIN BLAST
ncRNA	sulf1-005 (1) Ensembl	Ensembl	721 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations