Gene
cox8a
- ID
- ZDB-GENE-030131-9136
- Name
- cytochrome c oxidase subunit 8A
- Symbol
- cox8a Nomenclature History
- Previous Names
-
- coxXVIII (1)
- fb01d11
- hm:zehn2228
- wu:fb01d11
- zehn2228
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have cytochrome-c oxidase activity. Predicted to localize to mitochondrion and respiratory chain complex IV. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Is expressed in brain; gill; heart; liver; and skeletal muscle. Orthologous to several human genes including COX8A (cytochrome c oxidase subunit 8A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Little et al., 2010
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mitochondrial complex IV deficiency nuclear type 15 | Alliance | ?Mitochondrial complex IV deficiency, nuclear type 15 | 619059 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytochrome c oxidase, subunit 8 | Cytochrome c oxidase, subunit 8 superfamily |
|---|---|---|---|
|
UniProtKB:E9QFA6
|
76 |
Interactions and Pathways
No data available
Plasmids
No data available